Flavonoid compounds of low toxicity for biological imaging applications
US9636021B2 · kind B2 · utility
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15Claims
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Key dates
| Filing date | Jun 16, 2015 |
| Grant date | May 2, 2017 |
| Priority date | — |
| Expiry date | Jun 16, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/4603
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Flavonoid compounds that are selective for a protein, a portion or a living cell, or a portion of an organism may be used as biological imaging agents. The flavonoid compounds are useful for methods of imaging organisms such as zebrafish embryos and zebra fish. Flavonoid compounds may also be used to detect protein. Advantageously, flavonoids that selectively bind protein, a portion of a living cell, or a portion of an organism may exhibit a florescence “turn-on” mechanism, where the flavonoids that are selectively bound exhibit a florescence response when excited.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.