Prodrugs of compounds that enhance antifungal activity and compositions of said prodrugs
US9636298B2 · kind B2 · utility
1Cited by
46References
7Claims
0Family size
Inventors
Key dates
| Filing date | Jan 15, 2015 |
| Grant date | May 2, 2017 |
| Priority date | — |
| Expiry date | Jan 15, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to prodrugs for use in the inhibition of histone deacetylase. The prodrugs of the present invention have good aqueous solubility and good aqueous stability. The prodrugs of the invention advantageously are metabolized to the active ingredient in plasma or in the blood stream of a warm-blooded animal. The invention also provides compositions and, and methods for making the prodrugs, and methods for using the prodrugs to treat fungal infections.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.