Method for detecting a brain region with neurodegenerative change

US9636422B2 · kind B2 · utility

Assignee

• Siemens Aktiengesellschaft · DE

Inventors

• Thorsten Feiweier · Peising, DE
• Diana Martin · Herzogenaurach, DE
• Gunther Platsch · Haag in Oberbayern, DE
• Sebastian Schmidt · Weisendorf, DE
• Kristin Schmiedehausen · Buckenhof, DE
• Michael Szimtenings · Bonn, DE

Key dates

• Filing date: Jul 24, 2008
• Grant date: May 2, 2017
• Expiry date: Dec 10, 2035

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61B6/5247
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A computerized method is disclosed for detecting a brain region with neurodegenerative change and also a brain region with vascular change in the brain of a patient and also an imaging arrangement suitable for this. In at least one embodiment, the method includes recording a first data record of the brain via positron emission tomography and a second data record of the brain via magnetic resonance imaging; reconstructing a PET image from the first data record and an MRI image from the second data record; identifying evidence for a brain region with vascular change in the MRI image; segmenting the MRI image into gray matter and white matter; identifying a brain region with neurodegenerative change in the PET image; and superposing the PET image and the segmented MRI image to determine whether the brain region with neurodegenerative change is present in gray matter or in white matter, the recording of the first data record and the second data record being carried out in quick succession without repositioning the patient or is even carried out simultaneously.