Heterocyclic sulfone RORγ modulators
US9637455B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 5, 2015 |
| Grant date | May 2, 2017 |
| Priority date | — |
| Expiry date | Jan 5, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D405/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Described are RORγ modulators of the formula (I), [INSERT CHEMICAL STRUCTURE HERE] or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein all substituents are defined herein. Also provided are pharmaceutical compositions comprising the same. Such compounds and compositions are useful in methods for modulating RORγ activity in a cell and methods for treating a subject suffering from a disease or disorder in which the subject would therapeutically benefit from modulation of RORγ activity, for example, autoimmune and/or inflammatory disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.