Patent · US Active

Mirac proteins

US9637734B2 · kind B2 · utility

3Cited by
2References
30Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 4, 2014
Grant dateMay 2, 2017
Priority date
Expiry dateMar 4, 2034

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02A50/30
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

This disclosure relates to a method of generating conditionally active biologic proteins from wild type proteins, in particular therapeutic proteins, which are reversibly or irreversibly inactivated at the wild type normal physiological conditions. For example, evolved proteins are virtually inactive at body temperature, but are active at lower temperatures.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.