Method for evaluating redox activity of nucleic acid molecule and nucleic acid molecule having redox activity
US9637737B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 2, 2012 |
| Grant date | May 2, 2017 |
| Priority date | — |
| Expiry date | Dec 6, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2330/31
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides a novel technique by which the redox activity of a nucleic acid molecule can be evaluated. An evaluation method of the present invention includes: a detection step of electrochemically detecting a redox reaction to a substrate, the redox reaction being catalyzed by a nucleic acid molecule to be evaluated, using a device that electrochemically detects a redox reaction; and an evaluation step of evaluating redox activity of the nucleic acid molecule from a result of the detection of the redox reaction. As the device, a device in which a base provided with a detection portion is included, the detection portion includes an electrode system, and the nucleic acid molecule to be evaluated is arranged on the base is used. In the present invention, it is preferred that a plurality of kinds of nucleic acid molecule to be evaluated is arranged on the base, and the plurality of kinds of nucleic acid molecules to be evaluated is evaluated by a single device.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.