Quantifying magnetic resonance parameters
US9640069B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 31, 2014 |
| Grant date | May 2, 2017 |
| Priority date | — |
| Expiry date | Oct 17, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01R33/58
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Example apparatus and methods provide improved spatial and temporal resolution over conventional magnetic resonance imaging (MRI) for a large (e.g., 500 cm3) three dimensional (3D) volume. Example apparatus and methods reconstruct under-sampled 3D data associated with nuclear magnetic resonance (NMR) signals acquired from the volume using a 3D through-time non-Cartesian generalized auto-calibrating partially parallel acquisitions (GRAPPA) approach. The NMR signals are produced in response to a 3D non-Cartesian (e.g., stack-of-spirals) pulse sequence. Example apparatus and methods produce a quantified value for T1 relaxation, T2 relaxation, diffusion, or other NMR parameters in the volume from signal intensities in the data. The quantified value may describe, for example, a perfusion parameter, a blood flow parameter, a blood volume parameter, or other value. Greater precision is achieved for the NMR parameter in the volume as a result of the quantization performed on data acquired with greater spatial resolution and temporal resolution.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.