Process for preparing liquid mixtures of known pH and salt concentration
US9643103B2 · kind B2 · utility
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6Claims
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Key dates
| Filing date | May 24, 2011 |
| Grant date | May 9, 2017 |
| Priority date | — |
| Expiry date | Jun 28, 2033 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG05D11/02
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
A method of preparing a liquid mixture for use in a liquid chromatography system is provided. The mixture comprises one or more acids, one or more bases, one or more salts, and one or more solvents, and the method comprises the steps of: i) calculating pH and/or salt concentration at a particular time t from a user-determined gradient function; and ii) based on the values obtained in step (i), calculating percent acid, percent base, percent salt and percent solvent in the liquid mixture at time t. A liquid chromatography system incorporating such method is also provided.
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