Crystalline forms of {[1-cyano-5-(4-chlorophenoxy)-4-hydroxy-isoquinoline-3-carbonyl]-amino}-acetic acid

US9643928B2 · kind B2 · utility

Assignee

• FibroGen, Inc. · US

Inventors

• Claudia Witschi · San Francisco, US
• Michael D. Thompson · San Diego, US
• Jung Min Park · San Francisco, US
• Michael P. Arend · Foster City, US

Key dates

• Filing date: Jan 23, 2014
• Grant date: May 9, 2017
• Expiry date: Jan 23, 2034

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present disclosure relates to crystalline forms of {[1-cyano-5-(4-chlorophenoxy)-4-hydroxy-isoquinoline-3-carbonyl]-amino}-acetic acid (Compound A), the process of preparing crystalline forms of Compound A, the pharmaceutical compositions containing them, and the methods of use thereof.