Methods for the production of IPS cells using Epstein-Barr (EBV)-based reprogramming vectors
US9644184B2 · kind B2 · utility
4Cited by
10References
10Claims
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Key dates
| Filing date | Mar 11, 2013 |
| Grant date | May 9, 2017 |
| Priority date | — |
| Expiry date | Mar 26, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2840/206
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods and composition of induction of pluripotent stem cells and other desired cell types are disclosed. For example, in certain aspects methods for generating essentially vector-free induced pluripotent stem cells are described. Furthermore, the invention provides induced pluripotent stem cells and desired cell types essentially free of exogenous vector elements with the episomal expression vectors to express differentiation programming factors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.