Method to evaluate the tissue targeting of a molecule of interest
US9645138B2 · kind B2 · utility
5Cited by
2References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 25, 2014 |
| Grant date | May 9, 2017 |
| Priority date | — |
| Expiry date | Feb 25, 2034 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/5082
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention relates to a method for evaluating whether a molecule of interest binds or is incorporated in at least one target tissue, comprising visualizing and comparing the distribution of the molecule of interest and of at least one control compound within the target tissue or on the target tissue surface of at least one animal that has previously received the molecule of interest and/or the control compound. Advantageously, the distribution of the molecule of interest is visualized and compared with the distribution of positive and negative compounds using mass spectrometry imaging on the surface of the target tissue.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.