Methods for predicting the survival time of a patient suffering from a solid cancer

US9645152B2 · kind B2 · utility

Assignees

• Institut National de la Sante et de la Recherche Medicale (INSERM) · FR
• UNIVERSITÉ PARIS DESCARTES - PARIS V · FR
• ASSISTANCE PUBLIQUE—HÔPITAUX DE PARIS (APHP) · FR

Inventors

• Jerome Galon · Paris, FR
• Franck Pages · Paris, FR
• Herve Fridman · Paris, FR
• Bernhard Mlecnik · Paris, FR

Key dates

• Filing date: Aug 27, 2015
• Grant date: May 9, 2017
• Expiry date: Aug 27, 2035

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2800/52
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The present invention provides methods and kits for the prognosis of survival time of a patient suffering from a cancerous tumor. The method involves quantitating the density of Th17 cells at the center of the tumor and at the invasive margin of the tumor, where low density values at each location indicate a favourable prognosis, high values at each location indicate an unfavourable prognosis, and heterogeneous values at the two locations (one high, one low) indicate an intermediate prognosis.