Methods and systems for analysis of fibers and branching structures within an image of a sample
US9646194B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 28, 2013 |
| Grant date | May 9, 2017 |
| Priority date | — |
| Expiry date | Dec 22, 2033 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG06T2207/30024
- WIPO fieldComputer technology
- WIPO sectorElectrical engineering
Abstract
A computer-implemented method and system perform efficient and accurate fiber morphology analysis of fiber-containing biological samples. The images of objects comprising fiber and/or branching structure are obtained by camera and/or other imaging devices. Initial tracing seeds are obtained by variable modules. The adaptive threshold method is utilized for identifying tracing seeds candidates by local Principal Component Analysis (PCA) calculation and sorting out the seeds with low and high score. Each single fiber segment of interest is traced repeatedly utilizing PCA fitting calculation, and individual fiber segments are assembled by performing crossover matching calculation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.