Use of nitrite salts in chronic ischemia
US9649334B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Nov 17, 2008 |
| Grant date | May 16, 2017 |
| Priority date | — |
| Expiry date | Jun 8, 2029 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods of treating a subject who has chronic tissue ischemia are disclosed. The methods can include administering to the subject a pharmaceutical composition comprising inorganic nitrite or a pharmaceutically acceptable salt thereof, for a time and in an amount sufficient to result in blood vessel growth in the ischemic tissue. The subject can be diagnosed as having a medical condition that results in persistent or recurring restriction of blood supply to a tissue, for example, peripheral artery disease, diabetes, atherosclerotic cardiovascular disease or defective wound healing. The methods can include the step of identifying a suitable subject.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.