Method of improving transplant function using soluble complement receptor type I (sCR1)
US9649356B2 · kind B2 · utility
3Cited by
9References
7Claims
0Family size
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Key dates
| Filing date | Oct 27, 2011 |
| Grant date | May 16, 2017 |
| Priority date | — |
| Expiry date | Mar 6, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/705
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method is disclosed for inhibiting complement activation in brain-dead organ donors, particularly kidney donors, which leads to improvement of organ function of transplanted organs in recipients. The method involves administration of a complement inhibitory protein, specifically a soluble complement receptor type I (sCR1) polypeptide to the donor prior to harvesting the organ for transplant.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.