Multiple-sample microfluidic chip for DNA analysis
US9649631B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 4, 2011 |
| Grant date | May 16, 2017 |
| Priority date | — |
| Expiry date | Mar 1, 2034 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2021/4186
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Aspects of the disclosure provide a microfluidic chip. The microfluidic chip includes a first domain configured for polymerase chain reaction (PCR) amplification of DNA fragments, and a second domain for electrophoretic separation. The first domain includes at least a first reaction reservoir designated for PCR amplification based on a first sample, and a second reaction reservoir designated for PCR amplification based on a second sample. The second domain includes at least a first separation unit coupled to the first reaction reservoir to received first amplified DNA fragments based on the first sample, and a second separation unit coupled to the second reaction reservoir to received second amplified DNA fragments based on the second sample. The first separation unit is configured to perform electrophoretic separation for the first amplified DNA fragments, and the second separation unit is configured to perform electrophoretic separation for the second amplified DNA fragments.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.