N-(pyridin-2-yl)pyrimidin-4-amine derivatives containing a sulfoximine group

US9650361B2 · kind B2 · utility

Assignee

• Bayer Pharma Aktiengesellschaft · DE

Inventors

• Ulrich Lücking · Berlin, DE
• Niels Böhnke · Berlin, DE
• Arne Scholz · Berlin, DE
• Philip Lienau · Berlin, DE
• Gerhard Siemeister · Berlin, DE
• Ulf Bömer · Glienicke, DE
• Dirk Kosemund · Berlin, DE
• Rolf Bohlmann · Berlin, DE
• Ludwig Zorn · Berlin, DE

Key dates

• Filing date: Nov 13, 2013
• Grant date: May 16, 2017
• Expiry date: Nov 13, 2033

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to disubstituted N-(pyridin-2-yl)pyrimidin-4-amine derivatives containing a sulfoximine group of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I).