Antibacterial compounds and methods for use

US9650395B2 · kind B2 · utility

Assignee

• PTC THERAPEUTICS, INC. · US

Inventors

• Arthur Branstrom · Rockville, US
• Vara Prasad Venkata Nagendra Josyula · Ann Arbor, US
• Michael A. Arnold · Flemington, US
• Aleksey I. Gerasyuto · Flemington, US
• Gary Mitchell Karp · Princeton, US
• Jiashi Wang · Monmouth Junction, US
• Tamil Arasu · Edison, US
• John David Baird · Guelph, CA
• Wu Du · Cranbury, US
• Olya Ginzburg · Bloomfield, US
• Yi Jin Kim Gorske · Brunswick, US
• Jana Narasimhan · Scotch Plains, US
• Srinivasa Peddi · Piscataway, US
• Hongyan Qi · Plainsboro, US
• Sean Wesley Smith · Wantage, US
• Anthony Turpoff
• Richard Wilde · Newark, US
• Tianle Yang · Mountainside, US
• Nanjing Zhang · Princeton, US
• Xiaoyan Zhang · Lexington, US

Key dates

• Filing date: Aug 29, 2012
• Grant date: May 16, 2017
• Expiry date: Aug 29, 2032

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present description relates to compounds and forms and pharmaceutical compositions thereof and methods for use thereof to treat or ameliorate bacterial infections caused by wild-type and multi-drug resistant Gram-negative and Gram-positive pathogens.