Patent · US Active

Endonucleases

US9650618B2 · kind B2 · utility

0Cited by

2References

12Claims

0Family size

Assignee

Biotec Pharmacon Asa · NO

Inventors

Olav Lanes · Tromsø, NO
Linda Havdalen · Tromsø, NO
Terese Solstad · Halden, NO
Marit Sjo Lorentzen
Bjørn Altermark · Tromsø, NO
Ingar Leiros · Tromsø, NO
Ronny Helland · Tromsø, NO

Key dates

Filing date	Jul 15, 2016
Grant date	May 16, 2017
Priority date	—
Expiry date	Jul 15, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q2521/301
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present invention provides an endonuclease I or enzymatically active fragment thereof wherein said endonuclease I has the sequence of SEQ ID No. 4 or a sequence which is at least 70% identical thereto and wherein the amino acid residue which is immediately N-terminal of the FYCGC pentapeptide motif has been substituted with a residue which is negatively charged as well as nucleic acid molecules encoding these enzymes and methods of removing contaminating polynucleotides from a sample using these enzyme.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.