Compositions and methods for targeted nucleic acid sequence enrichment and high efficiency library regeneration
US9650628B2 · kind B2 · utility
18Cited by
203References
37Claims
0Family size
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Key dates
| Filing date | Jan 25, 2013 |
| Grant date | May 16, 2017 |
| Priority date | — |
| Expiry date | Jan 25, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2565/514
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides methods, compositions and kits for targeted nucleic acid sequence enrichment in a nucleic acid sample and for high efficiency nucleic acid library generation for next generation sequencing (NGS). Specifically, the methods, compositions and kits provided herein are useful for the production and capture of amplification-ready, target-specific and strand-specific regions of interest from nucleic acid samples containing complex DNA.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.