Detection of nucleotide variation on target nucleic acid sequence by PTO cleavage and extension assay
US9650665B2 · kind B2 · utility
0Cited by
6References
17Claims
0Family size
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Key dates
| Filing date | Feb 25, 2013 |
| Grant date | May 16, 2017 |
| Priority date | — |
| Expiry date | Jun 23, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6858
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention is generally drawn to a novel method and a kit for detecting nucleotide variations by a PTOCE (PTO Cleavage and Extension) assay with PTO-NV. Furthermore, the present invention is directed to a novel method and a kit for detecting a nucleotide variation on a target nucleic acid sequence by a PTOCE assay with PTO-NV having a non-base paring moiety.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.