Display of binding agents

US9651559B2 · kind B2 · utility

Assignee

• F-star Biotechnologische Forschungs- und Entwicklungsges M.B.H. · AT

Inventors

• Gottfried Himmler · Groß-Enzersdorf, AT
• Geert Mudde · Purkersdorf, AT
• Gerda Redl · Groß-Enzersdorf, AT
• Florian Ruker · Wien, AT
• Gordana Wozniak-Knopp · Wien, AT

Key dates

• Filing date: Dec 1, 2014
• Grant date: May 16, 2017
• Expiry date: Dec 1, 2034

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2333/70535
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The present application relates to a method of preparing a genetic package displaying oligomers of modular antibody domains binding to a target and to a scaffold ligand as well as to vectors and libraries of genetic packages produced thereby. The invention further relates to methods of selecting suitable linker sequences for use in such oligomer display.