Pharmaceutical composition and the use thereof, and application regime of said pharmaceutical composition for on-demand contraception

US9655887B2 · kind B2 · utility

Assignee

• Bayer Pharma Aktiengesellschaft · DE

Inventors

• Bernhard Lindenthal · Berlin, DE
• Nico Bräuer · Falkensee, DE
• Peter Serno · Bensberg, DE
• Andrea Rotgeri · Berlin, DE
• Ulrike Fuhrmann · Berlin, DE
• Bernd Buchmann · Hohen Neuendorf, DE
• Anne Mengel · Berlin, DE
• Ulrike Röhn · Berlin, DE
• Antonius Ter Laak · Berlin, DE

Key dates

• Filing date: May 16, 2014
• Grant date: May 23, 2017
• Expiry date: May 16, 2034

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to a pharmaceutical composition for non-hormonal, on-demand contraception and to processes for preparing this pharmaceutical composition. The latter comprises 2H-indazole as novel EP2 receptor antagonists in combination with COX inhibitors. The invention furthermore provides a method for non-hormonal female-controlled on-demand contraception where a pharmaceutical composition comprising EP2 receptor antagonists in combination with COX inhibitors is taken on demand prior to expected sexual intercourse.