Chimeric nucleic acid molecules with non-AUG translation initiation sequences and uses thereof
US9655956B2 · kind B2 · utility
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53Claims
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Key dates
| Filing date | Jul 28, 2016 |
| Grant date | May 23, 2017 |
| Priority date | — |
| Expiry date | Jul 28, 2036 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure relates to nucleic acid vaccine compositions and methods for preventing or treating pathological conditions, such as cancer or infectious disease. Further, the disclosure provides methods for more efficient production of antigens via mRNA containing one or more non-conventional start codons to promote multiplex initiation of translation in eukaryotic cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.