Patent · US Active

System and method to separate cells and/or particles

US9656263B2 · kind B2 · utility

32Cited by

4References

15Claims

0Family size

Assignee

ACOUSORT AB · SE

Inventors

Thomas Laurell · Lund, SE
Carl Grenvall · Lund, SE
Cecilia Magnusson · Malmö, SE
Per Augustsson · Handen, SE

Key dates

Filing date	Sep 27, 2012
Grant date	May 23, 2017
Priority date	—
Expiry date	Sep 27, 2032

Classification

Technology area (CPC G)Physics
CPC primaryG01N2015/0053
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The invention provides a micro scaled method and system for separating a subgroup of cells and/or particles from a mixture of different types of cells and/or particles in a suspension. The suspension is forced under pressure into an inlet and further into a pre-alignment channel wherein the suspension is subjected to a two dimensional acoustic force directed perpendicular to the length direction of the pre-alignment channel. The suspension is then forced into a second inlet and further into at least one separation channel wherein the mixture of cells and/or particles are forced towards the walls of the channel and subjected to a one dimensional acoustic force directed perpendicular to the length direction of the separation channel. Cells and/or particles having the same size and/or mass density and/or compressibility are collected through at least two outlets.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.