Patent · US Active

5-(trifluoromethyl)pyrimidine derivatives and method for producing same

US9656970B2 · kind B2 · utility

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7Claims

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Assignee

TOSOH F-TECH, INC. · JP

Inventors

Takumi Kagawa · Nanyo, JP
Daiki Shigehiro · Yamaguchi, JP
Kosuke Kawada · Kudamatsu, JP

Key dates

Filing date	Apr 23, 2015
Grant date	May 23, 2017
Priority date	—
Expiry date	Apr 23, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D239/38
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Provided are 5-(trifluoromethyl)pyrimidine derivatives useful as intermediates for pharmaceuticals and agrochemicals and as intermediates for electronic materials and methods for producing the same. 2,4-dichloro-5-(trifluoromethyl)pyrimidine is reacted with 2,2,2-trifluoroethanol, benzyl alcohol, or benzenethiol to obtain the intended 2-(2,2,2-trifluoroethoxy)-4-chloro-5-(trifluoromethyl)pyrimidine, 2-benzyloxy-4-chloro-5-(trifluoromethyl)pyrimidine, 2,4-bis(2,2,2-trifluoroethoxy)-5-(trifluoromethyl)pyrimidine, or 2-chloro-4-phenylthio-5-(trifluoromethyl)pyrimidine.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.