Fusion protein inhibiting angiogenesis or growth and use thereof
US9657084B2 · kind B2 · utility
18Cited by
2References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 23, 2015 |
| Grant date | May 23, 2017 |
| Priority date | — |
| Expiry date | Jan 23, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/35
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are a fusion protein inhibiting angiogenesis or vascular growth, coding sequence thereof, vector comprising the coding sequence, host cell, pharmaceutical composition and use of the fusion protein. The fusion protein of the present invention has high thermostability, and has a dramatic decline in the protein aggregation formation rate in a fermentation process, and a significant increase in the purity and yield of the protein, and has better biological activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.