Lentiviral vectors containing an MHC class I, MHC class II, or B2 microglobulin upstream promoter sequence
US9657311B2 · kind B2 · utility
3Cited by
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21Claims
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Key dates
| Filing date | May 27, 2014 |
| Grant date | May 23, 2017 |
| Priority date | — |
| Expiry date | May 27, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2830/85
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to the insertion of an MHC class I, MHC Class II, or β2 microglobulin upstream promoter sequence into a lentiviral vector to increase viral titers. The invention encompasses these vectors, methods of making the vectors, and methods of using them, including medicinal uses.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.