Methods for modulating thermostability and acid tolerance of microbes
US9657328B2 · kind B2 · utility
0Cited by
2References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 11, 2009 |
| Grant date | May 23, 2017 |
| Priority date | — |
| Expiry date | Jan 13, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N9/1029
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to a method for modulating thermostability or acid tolerance of a microbe by mutating a nucleic acid molecule encoding a homoserine o-succinyltransferase (MetA) to obtain a nucleic acid molecule encoding a mutant MetA and transforming a microbial cell with the nucleic acid molecule encoding a mutant MetA. The microbe, a bacteria expressing the mutant MetA of the present invention represents a growth rate improved in a vigorous environment such as higher-temperatures and/or lower pH conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.