Patent · US Active

Probes for improved melt discrimination and multiplexing in nucleic acid assays

US9657332B2 · kind B2 · utility

3Cited by

9References

17Claims

0Family size

Assignee

LUMINEX CORPORATION · US

Inventors

Doug WHITMAN · Round Rock, US
Nicolas Arab · Austin, US
Chuck Collins · Austin, US

Key dates

Filing date	Aug 11, 2014
Grant date	May 23, 2017
Priority date	—
Expiry date	Dec 31, 2034

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q1/6818
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Methods and compositions for the detection and quantification of nucleic acids are provided. In certain embodiments, methods involve the use of primers or probes that comprise a non-natural nucleotide linked to a reporter. Target nucleic acids are detected by the polymerization of a complementary probe or primer that incorporated a cognate non-natural nucleotide linked to a quencher.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.