Assaying substrate with surface-enhanced raman scattering activity
US9658163B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 4, 2010 |
| Grant date | May 23, 2017 |
| Priority date | — |
| Expiry date | Aug 3, 2033 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/553
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A metal substrate obtained by agglomerating 5 nm to 100 nm metal nano-particles (including clusters) having SERS activity on a metal substrate having a lower electrode potential (higher ionization tendency) than the electrode potential of the metal nano-particles, and fixing the metal nano-particles in an optimally agglomerated state that acts as hot sites, when a detection specimen is adsorbed in a non-dried state, and a predetermined laser light is irradiated, the surface enhanced Raman scattered (SERS) light of antigen detection specimen can be detected by surface Raman resonance in an optimally agglomerated state.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.