Dry powder drug delivery system and methods

US9662461B2 · kind B2 · utility

Assignee

• MannKind Corporation · US

Inventors

• Chad C. Smutney · Watertown, US
• Benoit Adamo · Mount Kisco, US
• John M. Polidoro · Coventry, US
• P. Spencer Kinsey · Sandy Hook, US
• Dennis Overfield · Fairfield, US
• Carl R. Sahi · Coventry, US
• Christine Billings · Danbury, US
• Mark T. Marino · Danbury, US

Key dates

• Filing date: May 2, 2016
• Grant date: May 30, 2017
• Expiry date: May 2, 2036

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61M2205/6081
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

A pulmonary drug delivery system is disclosed, including a breath-powered, dry powder inhaler, and a cartridge for delivering a dry powder formulation. The inhaler and cartridge can be provided with a drug delivery formulation comprising, for example, a diketopiperazine and an active ingredient, including, small organic molecules, peptides and proteins, including, insulin and glucagon-like peptide 1 for the treatment of disease and disorders, for example, endocrine disease such as diabetes and/or obesity.