Biaryl acyl-sulfonamide compounds as sodium channel inhibitors
US9663508B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 1, 2014 |
| Grant date | May 30, 2017 |
| Priority date | — |
| Expiry date | Oct 1, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D405/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides compounds of Formula (Ia), and pharmaceutically acceptable salts thereof. The compounds are useful as inhibitors of voltage-gated sodium channels, in particular Nav 1.7.as described in the specification. The compounds are useful for the treatment of diseases treatable by inhibition of sodium channels such as pain disorders. Also provided are pharmaceutical compositions containing compounds of the present invention, as well as intermediates and processes useful for making the compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.