System and method of detection and quantification by mass spectrometry and by activating ionised molecular species
US9666420B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Jun 24, 2014 |
| Grant date | May 30, 2017 |
| Priority date | — |
| Expiry date | Jun 24, 2034 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N30/7266
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed is a system and method of mass spectrometry, including: a. ionizing an analyte to form a precursor ion (A) having a mass-to-charge ratio (m/z), in which m represents the mass and z the electric charge number; b. activating the precursor ion (A) by interaction with a beam of neutral species, ions, electrons or photons, having an energy chosen on the basis of the physicochemical properties of the precursor ion, the activation being suitable for producing a product ion (B, C) having the same mass m as the precursor ion (A) and an electric charge number z′ such that z′ is a non-zero integer different from z; c. separating the product ion (B, C, E, F) having a predefined mass-to-charge ratio (m/z′); d. detecting the product ion (B, C) having the predefined mass-to-charge ratio (m/z′).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.