4-aryl-N-phenyl-1,3,5-triazin-2-amines containing a sulfoximine group

US9669034B2 · kind B2 · utility

Assignee

• Bayer Intellectual Property GmbH · DE

Inventors

• Ulrich Lücking · Berlin, DE
• Rolf Bohlmann · Berlin, DE
• Arne Scholz · Berlin, DE
• Gerhard Siemeister · Berlin, DE
• Mark Jean Gnoth · Mettmann, DE
• Ulf Bömer · Glienicke, DE
• Dirk Kosemund · Berlin, DE
• Philip Lienau · Berlin, DE
• Gerd Ruhter · Hamburg, DE
• Carsten Schultz-Fademrecht · Pomezia, IT

Key dates

• Filing date: May 21, 2012
• Grant date: Jun 6, 2017
• Expiry date: May 21, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07B2200/05
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to 4-aryl-N-phenyl-1,3,5-triazin-2-amines containing a sulfoximine group of general formula (I) or (Ia) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I) or (Ia).