Modulation of reactivation of a latent virus
US9669036B2 · kind B2 · utility
10Cited by
1References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 14, 2014 |
| Grant date | Jun 6, 2017 |
| Priority date | — |
| Expiry date | May 14, 2034 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K45/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The disclosure relates to methods of controlling the state of a virus (lytic or lysogenic) in an individual, such as a method of reactivating a latent virus in an individual, comprising administering one or more agents that modulates the activity of signal transducer and activator of transcription 3 (STAT3) or any of p300, CBP or p300/CBP. Also contemplated are methods further comprising administering an HDAC modulating agent, such as an HDAC inhibiting agent or an HDAC activating agent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.