Polymer support for the distribution of a naturally crystalline substance and production method
US9669100B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 10, 2014 |
| Grant date | Jun 6, 2017 |
| Priority date | — |
| Expiry date | Feb 10, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08J2377/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to the implementation of a method for loading, without a vehicle, a naturally crystalline substance solubilized by a solvent mixture in a lipophilic medium in a mixture of granulated polymers, for forming, without a plasticizer, a polymer support for the long-term controlled distribution of the naturally crystalline substance in the stable solubilized state, without permanent crystallization on the surface of said support. Said substance according to the invention can be insecticides and pesticides of the group of pyrethroids (e.g. deltamethrin), formamidines (e.g. amitraz) and carbamates (e.g. propoxur), or the mixture thereof, or cosmetics of the group of alkaloids (e.g. caffeine), or medicaments (e.g. ibuprofen). The permanent non-crystallization state on the surface of the polymer support is only ensured when said substance is solubilized in the solvent mixture consisting of an oxygenated solvent of dibasic esters of methylenic fatty acids and an oxygenated methylenic cosolvent in an active lipophilic solution incorporated into a polymer mixture consisting of a polyether block amide (PEBA) and a thermoplastic polyurethane elastomer (TPU). Said support can …
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.