Patent · US Active

Compositions comprising fusion variants of FGF19 polypeptides

US9670260B2 · kind B2 · utility

33Cited by
55References
28Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 29, 2015
Grant dateJun 6, 2017
Priority date
Expiry dateDec 29, 2035

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N33/66
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention relates to variants and fusions of fibroblast growth factor 19 (FGF19), variants and fusions of fibroblast growth factor 21 (FGF21), fusions of fibroblast growth factor 19 (FGF19) and/or fibroblast growth factor 21 (FGF21), and variants or fusions of fibroblast growth factor 19 (FGF19) and/or fibroblast growth factor 21 (FGF21) proteins and peptide sequences (and peptidomimetics), having one or more activities, such as glucose lowering activity, and methods for and uses in treatment of hyperglycemia and other disorders.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.