Production method for cell populations
US9670459B2 · kind B2 · utility
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6Claims
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Key dates
| Filing date | Aug 9, 2011 |
| Grant date | Jun 6, 2017 |
| Priority date | — |
| Expiry date | Dec 24, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2510/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention addresses the problem of providing cell populations having a high proportion of CD4-positive naive T cells and/or CD4-positive central memory T cells, and a production method thereof. The present invention provides a production method for CD4-positive T cell populations which is characterized by using anti-CD3 antibodies, fibronectin fragments, and Interleukin-4. The method is characterized not only by the attainment of a cell group with a high proportion of CD4-positive naive T cells and/or CD4-positive central memory T cells, but also by a high bulk yield.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.