Production of acetyl-coenzyme A derived compounds
US9670518B2 · kind B2 · utility
3Cited by
4References
14Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | May 9, 2012 |
| Grant date | Jun 6, 2017 |
| Priority date | — |
| Expiry date | May 9, 2032 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02E50/10
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present disclosure relates to the use of pantothenate compounds as a non-genetic switch for the production of heterologous acetyl-CoA derived (HACD) compounds in microbial host cells. The invention provides genetically modified microorganisms that are more stable when stored and initially cultured under reduced pantothenate concentrations, cell culture media having reduced concentrations of pantothenate compounds, and methods of producing HACD compounds using the cell culture media and the genetically engineered microorganisms of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.