Patent · US Active

Concentrating a target molecule for sensing by a nanopore

US9670526B2 · kind B2 · utility

18Cited by
3References
13Claims
0Family size

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Key dates

Filing dateNov 8, 2013
Grant dateJun 6, 2017
Priority date—
Expiry dateNov 8, 2033

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N33/54373
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

Methods and related products are disclosed that improve the probability of interaction between a target molecule and a nanopore by capturing the target molecule on a surface comprising the nanopore. The captured target molecule, the nanopore, or both, are able to move relative to each other along the surface. When the leader of the target molecule is in proximity with the nanopore, interaction of the target portion of the target molecule with the nanopore occurs, thereby permitting sensing of the target portion. Confining the target molecule and nanopore in this manner leads to significantly enhanced interaction with the nanopore.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.