Beclin 1 phosphorylation
US9671412B2 · kind B2 · utility
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18Claims
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Key dates
| Filing date | Mar 24, 2015 |
| Grant date | Jun 6, 2017 |
| Priority date | — |
| Expiry date | Jun 17, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/52
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Antibodies specific for human Beclin 1 protein phosphorylated Ser234, Ser295, Tyr229, Tyr233 or Try352 are useful in diagnosing diseases such as cancer and impaired autophagy. The invention further relates to human Beclin 1 mutated at Ser234, Ser295, Tyr229, Tyr233 or Try352 with a phospho-silencing residue and uses thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.