Patent · US Active

Polyenolic zinc-binding agents (pezbins) actively promote inactivation of cancer stem cells and potentiate cytotoxic anti-tumor drug substances

US9675576B2 · kind B2 · utility

3Cited by

6References

20Claims

0Family size

Assignees

The Research Foundation for The State University of New York · US
Chem-Master International, Inc. · US

Inventors

Lorne M. Golub · Smithtown, US
Francis Johnson · Setauket, US
Galina I. Botchkina · Stony Brook, US
Iwao Ojima · Port Jefferson, US

Key dates

Filing date	Nov 24, 2015
Grant date	Jun 13, 2017
Priority date	—
Expiry date	Nov 24, 2035

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P35/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides a method of inhibiting the growth of or promoting differentiation and destruction of cancer stem cells (CSCs) comprising contacting the cancer stem cells with a compound having the structure:or a pharmaceutically acceptable salt thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.