Compositions of tolperisone

US9675598B2 · kind B2 · utility

Assignee

• SANOCHEMIA PHARMAZEUTIKA AG · AU

Inventors

• Federico Gaeta · Carrión de los Condes, ES
• Klaus Gerdes · Düsseldorf, DE
• Stefan Welzig · Wien, AT
• Beate Katz · Steinbrunn, AT
• Jan Rothenburger · Eisenstadt, AT
• Jozsef Gungl · Ágfalva, HU

Key dates

• Filing date: Aug 1, 2016
• Grant date: Jun 13, 2017
• Expiry date: Aug 1, 2036

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T436/145555
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present disclosure relates to tolperisone, or a pharmaceutically acceptable salt or hydrate thereof, with 10 ppm 2-methyl-1-(4-methylphenyl)-propenone (4-MMPPO) or less, methods of producing the same, as well as compositions related thereto. The disclosure further relates to methods of treating a subject with tolperisone under conditions that limit exposure of the subject to tolerable levels of 4-MMPPO.