Methods for detecting modification resistant nucleic acids

US9677068B2 · kind B2 · utility

Assignee

• The Regents of the University of California · US

Inventors

• Jonathan Weissman · San Francisco, US
• Nicholas Ingolia · San Francisco, US
• Sina Ghaemmaghami · San Francisco, US
• John-Rhys Newman · Calabasas, US

Key dates

• Filing date: Feb 5, 2016
• Grant date: Jun 13, 2017
• Expiry date: Feb 5, 2036

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C40B50/06
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Methods are provided for, inter alia, detecting nucleic acid molecules resistant to degradation, such as a plurality of RNA molecules bound to a ribosome, using various technologies including deep sequencing.