Blocking reagent and methods for the use thereof

US9677131B2 · kind B2 · utility

Assignee

• Olink Proteomics AB · SE

Inventors

• Simon Fredriksson · Stockholm, SE
• Bonnie Tran · Uppsala, SE

Key dates

• Filing date: Jul 13, 2011
• Grant date: Jun 13, 2017
• Expiry date: Oct 31, 2033

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N33/54393
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The present invention relates to the use of a conjugate of a non-analyte-specific binding protein coupled to a nucleic acid as a blocking reagent in a probe-based detection assay, which uses a probe comprising a proteinaceous analyte-binding partner coupled to a nucleic acid domain to detect an analyte in a sample.