Biological tissue analysis by inverse spectroscopic optical coherence tomography
US9678007B2 · kind B2 · utility
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21Claims
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Key dates
| Filing date | Oct 12, 2012 |
| Grant date | Jun 13, 2017 |
| Priority date | — |
| Expiry date | Feb 21, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01B9/02091
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method and system to measure and image the full optical scattering properties by inverse spectroscopic optical coherence tomography (ISOCT) is disclosed. Tissue is modeled as a medium with continuous refractive index (RI) fluctuation and such a fluctuation is described by the RI correlation functions. By measuring optical quantities of tissue (including the scattering power of the OCT spectrum, the reflection albedo α defined as the ratio of scattering coefficient μs, and the backscattering coefficient μb), the RI correlation function can be inversely deduced and the full set of optical scattering properties can be obtained.
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