Bis-biotinylation tags
US9678080B2 · kind B2 · utility
27Cited by
18References
8Claims
0Family size
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Key dates
| Filing date | Jun 12, 2014 |
| Grant date | Jun 13, 2017 |
| Priority date | — |
| Expiry date | Jan 24, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/36
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Multi-biotinylated reactants are provided which can be used in divalent complexes for various applications such as colocalization, labeling, immobilization, and purification. Methods for constructing, purifying, and using the bis-biotinylated reactants are also provided. In certain embodiments, two bis-biotinylated reactants are bound to a single streptavidin tetramer to provide a complex having a 1:1 stoichiometry with respect to the bis-biotinylated reactants.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.