Patent · US Active

Transdermal therapeutic system for extended dosing of pramipexole in treating neurological disorders

US9682068B2 · kind B2 · utility

1Cited by

33References

25Claims

0Family size

Assignee

Mylan Inc. · US

Inventors

Abhijit Deshmukh · Malkajgiri, IN
Akhilesh Dixit · Secunderabad, IN
Prasanna Kumar · Frisco, US
Vikram Bindra · Panipat, IN

Key dates

Filing date	May 19, 2014
Grant date	Jun 20, 2017
Priority date	—
Expiry date	May 19, 2034

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61F2013/0296
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

This disclosure relates to a transdermal therapeutic system (TTS) containing pramipexole or related compounds and methods of making the system as well as its use in administering such compounds as a single dose over an extended period, for example, one week. The system comprises an acrylic-based or silicone-based matrix layer containing pramipexole at concentrations of at least about 5 wt. % of the matrix, which is resistant to crystallizing and discoloration of the active ingredient even when stored over long periods.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.