Patent · US Active

Amino-substituted isothiazoles

US9682995B2 · kind B2 · utility

0Cited by

0References

15Claims

0Family size

Assignee

Bayer Pharma Aktiengesellschaft · DE

Inventors

Lars Bärfacker · Oberhausen, DE
Stefan Prechtl · Berlin, DE
Gerhard Siemeister · Berlin, DE
Antje Margret Wengner · Berlin, DE
Jens Ackerstaff · Mülheim an der Ruhr, DE
Katrin Nowak-Reppel · Leverkusen, DE
Benjamin Bader · Berlin, DE
Philip Lienau · Berlin, DE
Detlef STÖCKIGT · Potsdam, DE
Tobias Heinrich · Berlin, DE

Key dates

Filing date	Jan 28, 2014
Grant date	Jun 20, 2017
Priority date	—
Expiry date	Jan 28, 2034

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D513/04
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The present invention relates to isothiazoles of general formula (I) which inhibit the mitotic checkpoint: in which A, R1 and R2 are as defined in the claims, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of neoplasms, as a sole agent or in combination with other active ingredients.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.